The milestone was achieved as Atletico Madrid hosted Alaves at the Riyadh Air Metropolitano on Saturday.
Simeone, who took over as Atletico’s head coach in December 2011, has firmly established himself as the most successful manager in the club’s history.
Under his leadership, Atletico have secured eight major trophies, including two La Liga titles in 2014 and 2021, two Europa League victories in 2012 and 2018, and two Champions League finals appearances.
Saturday’s match marked Simeone’s 492nd La Liga game at the helm of Atletico, a record for the most La Liga games managed by any coach at a single club.
He also ranks third for the most Champions League games managed with a single club, having overseen 109 matches, behind only Sir Alex Ferguson at Manchester United and Arsene Wenger at Arsenal.
Simeone’s tenure has been marked by consistency and success, with his team currently on a four-match winning streak across all competitions.
Atletico Madrid secured a hard-fought 2-1 victory against Alaves which not only secured another crucial three points but also brought up his 300th La Liga win as Atletico’s manager, adding to his already remarkable legacy.
At 54 years old, Simeone continues to push Atletico Madrid to new heights, ensuring his place as one of the most influential figures in Spanish football.